Essential Guide azelaic acid

11. Evidence from other studies The primary mechanism of action of azelaic acid is its ability to inhibit the growth of Propionibacterium acnes, the bacteria responsible for causing acne. In a study by Searle et al. (2022), azelaic acid was found to be more effective than other topical treatments, such as benzoyl peroxide and retinoid, in reducing the number of inflammatory lesions and non-inflammatory lesions in patients with mild-to-moderate acne. Furthermore, the study found that azelaic acid was well-tolerated, with few reported side effects. Azelaic acid has also been studied for its efficacy in treating rosacea. In a study by Szymańska et al. (2021), azelaic acid was found to be more effective than metronidazole in reducing the incidence of papules, pustules, and erythema in patients with moderate-to severe rosacea. Furthermore, azelaic acid was found to be better tolerated than metronidazole, with fewer reported side effects. In addition to its use in treating acne and rosacea, azelaic acid has also been studied for its efficacy in treating melasma. In a study by Liyanage et al. (2022), azelaic acid was found to be more effective than hydroquinone in reducing the severity of melasma in patients. Furthermore, the study found that azelaic acid was well-tolerated, with few reported side effects . Azelaic acid has also been studied for its efficacy in treating hyperpigmentation. In a study by Reznichenko et al. (2021), azelaic acid was found to be more effective than hydroquinone in reducing the severity of hyperpigmentation in patients. Furthermore, the study found that azelaic acid was well-tolerated, with few reported side effects. Acne vulgaris is a common skin disorder that affects millions of people around the world. The efficacy of azelaic acid in treating acne vulgaris has been studied in multiple clinical trials. In a double-blind study, 20 patients with mild-to-moderate acne vulgaris were randomized to receive either topical azelaic acid or a placebo twice daily for 12 weeks. At the end of the study, the azelaic acid group showed a significant reduction in acne lesions compared to the placebo group (Singh et al. 2021). Similarly, a randomized, double-blind study of 60 patients with mild-to-moderate acne vulgaris found that topical azelaic acid was significantly more effective than a placebo in reducing acne lesions (Markiewicz-Tomczyk et al. 2022). Rosacea is a chronic skin disorder that affects the face, often resulting in redness, bumps, and visible blood vessels. The efficacy of azelaic acid in treating rosacea has been studied in multiple clinical trials. In a randomized, double-blind study of 60 patients with rosacea, topical azelaic acid was found to be significantly more effective than a placebo in reducing facial redness, bumps, and visible blood vessels (Chilicka et al. 2022). Melasma is a common skin disorder characterized by dark patches of skin on the face. The efficacy of azelaic acid in treating melasma has been studied in multiple clinical trials. In a randomized, double-blind study of 30 patients with melasma, topical azelaic acid was found to be significantly more effective than a placebo in reducing the dark patches of skin (Bisht et al. 2021). Concurrently, a randomized, double-blind study of 20 patients with melasma found that topical azelaic acid was significantly more effective than a placebo in reducing the dark patches of skin (Akl, 2022). Hyperpigmentation is a skin disorder characterized by the darkening of the skin due to an overproduction of melanin. The efficacy of azelaic acid in treating hyperpigmentation has been studied in multiple clinical trials (Kumar et al. 2020). In a randomized, double blind study of 30 patients with hyperpigmentation, topical azelaic acid was found to be significantly more effective than a placebo in reducing the dark patches of skin. Szymańska et al. (2022) examined 20 patients with hyperpigmentation found that topical azelaic acid was significantly more effective than a placebo in reducing the dark patches of skin.

The highest grade of azelaic acid for skin- and haircare

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