Azeco Cosmeceuticals

AZECO COSMECEUTICALS BV - MUSSENBERG 1, 6049 GZ Herten, The Netherlands – Phone: +31 475 782540

Assumes elevated process temperature up to 40.0 °C

13. ES 13: U SE AS L ABORATORY C HEMICAL BY P ROFESSIONAL W ORKER

13.1. T ITLE SECTION

Laboratory Chemicals (PC 21) Manufacture of fine chemicals (SU 9) Formulation [mixing] of preparations and/or re-packaging (excluding alloys) (SU 10) E NVIRONMENT Contributing Scenario 1 : Use in laboratories

ERC 8a

W ORKER Contributing Scenario 2 : Roller application or brushing

PROC 10

Contributing Scenario 3 : Use as laboratory agent

PROC 15

13.2. C ONDITIONS OF USE AFFECTING EXPOSURE

13.2.1. C ONTROL OF ENVIRONMENTAL EXPOSURE : U SE IN LABORATORIES (ERC 8 a )

In consideration of the chemical safety assessment, performed for this substance according to Article 14 (3) of the REACH regulation, all identified uses of azelaic acid are assessed as safe for the environment.

13.2.2. C ONTROL OF WORKER EXPOSURE : R OLLER APPLICATION OR BRUSHING (PROC 10)

P RODUCT ( ARTICLE ) CHARACTERISTICS Covers percentage substance in the product up to 100 % A MOUNT USED ( OR CONTAINED IN ARTICLES ), FREQUENCY AND DURATION OF USE / EXPOSURE Covers daily exposures up to 8 hours T ECHNICAL AND ORGANISATIONAL CONDITIONS AND MEASURES Provide a good standard of general ventilation (not less than 3 to 5 air changes per hour) Local exhaust ventilation - efficiency of at least 80.0 % Basic (professional) exposure controls assumed C ONDITIONS AND MEASURES RELATED TO PERSONAL PROTECTION , HYGIENE AND HEALTH EVALUATION Wear suitable gloves tested to EN374 O THER CONDITIONS AFFECTING WORKERS EXPOSURE Indoor use Assumes elevated process temperature up to 40.0 °C P RODUCT ( ARTICLE ) CHARACTERISTICS Covers percentage substance in the product up to 100 % A MOUNT USED ( OR CONTAINED IN ARTICLES ), FREQUENCY AND DURATION OF USE / EXPOSURE Covers daily exposures up to 8 hours T ECHNICAL AND ORGANISATIONAL CONDITIONS AND MEASURES 13.2.3. C ONTROL OF WORKER EXPOSURE : U SE AS LABORATORY AGENT (PROC 15)

REGULATION (EC) No 1907/2006 Date of Issue: 02/01/2020

Page 55 of 56

Date of Revision: - AZCO99 Revision Nr.: - Version Nr.: 1