SERRA-BADRICH - HUMAN MICROBIOME (ROSACEA, ATOPIC DERMATITIS
An early interaction between the microbiome and immune system via multiple routes (skin–gut–lung) could feasibly affect the risk of a subsequent development of atopic diseases. We understand that the composition of the fungal community may be important in AD, yet we do not know how this pattern changes in flares. Understanding the complex interactions of the human microbiome will aid the development of novel and more targeted treatments to modulate the microbiome and influence AD outcomes. Principles gleaned from the success of faecal transplantation in the treatment of C. difficile infections may be translated to AD with organism transplantation used to normalise the skin or gut of those with, or at high risk of developing AD.
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