Essential Guide azelaic acid

Applications / Skin prone to acne The results indicate that the antibacterial activity of Azelaic acid is associated with the perturbation of intracellular pH of the organisms. The use of Azelaic acid as anti-acne ingredient is highly favourable compared to the traditional anti-acne ingredients, as the side effects are minimal and can easily be controlled by adjustment of the concentration Azelaic acid in the cream or gel.

APPLICABILITY

PRODUCTS FOR TREATMENT OF ACNE VULGARIS

COSMETIC USE

MEDICAL DEVICE USE

PHARMACEUTICAL USE

Azelaic acid

++

++

++

BENZOYL PEROXIDE

-

-

+

RETINOIDS

+/-

+/-

+

Α -HYDROXY ACIDS

++

++

++

ADAPALENE

-

-

++

TAZAROTENE

-

-

++

SALICYLIC ACID

+

+

+

SULPHUR

+

+

+

ANTIBIOTICS

-

-

+

TABLE 2: Legend: (++ Strongly recommended / Very suitable) (+ Limited recommended / Suitable) (+/- Limited allowed / Limited suitable) (- Forbidden)

FUNCTIONALITY

PRODUCTS FOR TREATMENT OF ACNE VULGARIS

COSMETIC USE

MEDICAL DEVICE USE

PHARMACEUTICAL USE

Azelaic acid

+

+

++

BENZOYL PEROXIDE

-

+/-

+/-

RETINOIDS

+/-

+/-

+

Α -HYDROXY ACIDS

-

-

-

ADAPALENE

-

-

++

TAZAROTENE

-

-

++

SALICYLIC ACID

+/-

+/-

+

SULPHUR

+

+/-

+/-

ANTIBIOTICS

-

-

+

TABLE 3: Legend: (++ Strongly recommended / Very suitable) (+ Limited recommended / Suitable) (+/- Limited allowed / Limited suitable) (- Forbidden)

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