Essential Guide azelaic acid

Applications / Anti-rosacea

4.2 Azelaic acid and anti-rosacea products Azelaic acid has been demonstrated to be effective for the treatment of rosacea. It helps reduce inflammatory lesions and erythema in rosacea patients. A major advantage of Azelaic acid is that it lacks the common side effects often associated with pharmaceutical treatments. Azelaic acid works by reducing inflammation, decreasing the number of bacteria on the skin, and lowering the production of keratin—a protein that can block pores and cause acne. These combined effects help alleviate redness, flushing, and other symptoms related to rosacea. It is available in various forms, including creams, gels, and lotions. Azelaic acid is considered an effective and well-tolerated treatment for rosacea. Products used for the treatment of rosacea Rosacea is a common, chronic, and incurable skin condition that often resembles acne. It primarily affects the central part of the face, especially the nose. Outbreaks of rosacea can, to some extent, be predicted based on certain triggers. Typical symptoms include persistent facial redness, tiny red pimples, and fine red lines known as telangiectasia (commonly referred to as spider veins). These spider veins are small, dilated blood vessels located near the surface of the skin and may also appear on other parts of the body, such as the arms and legs. A more severe manifestation of rosacea is rhinophyma, which presents as an enlarged, bulbous, and red nose. Treatment options for rosacea are limited. Aside from Azelaic acid and certain flavonoids, most available treatments are pharmaceutical in nature.

APPLICABILITY

PRODUCTS FOR TREATMENT OF ROSACEA

COSMETIC USE

MEDICAL DEVICE USE

PHARMACEUTICAL USE

++

++

+

Azelaic acid

BRIMONIDINE

–

–

++

METRONIDAZOLE

–

–

+

Α -HYDROXY ACIDS (AHAS)

+

+/-

+/-

ORAL ANTIBIOTICS

–

–

+

–

–

++

ISOTRETINOIN

ALTERNATIVE THERAPIES

+/-

+/-

+

TABLE 5: Legend: (++ Strongly recommended / Very suitable) (+ Limited recommended / Suitable) (+/- Limited allowed / Limited suitable) (- Forbidden)

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