Azeco Cosmeceuticals

Suppliers : [1] Dupont / Danisco Finnfeeds Oy [2] Croda Oleochemicals [3] Clariant / Nipa Preservatives [4] BASF / Cognis [5] Matrìca

Cream Specifications: Appearance

soft cream

Colour Odour

white

characteristic

pH

4,9 – 5,6

Typical:

5,2

Brookfield Viscosity (S4, 20 rpm, 25°C)

3,500 – 4,400 mPas

Typical:

3,850 mPas

Manufacturing instructions: 1.

The water phase (Phase A) is prepared by combining the ingredients. The water phase shall be alkaline as to (partially) ne tralise azelaic acid present in the oil phase. Ignoring to do so will inhibit emulsion formation. The water phase is heated to 70-75°C.

2. The oil phase (Phase B) is made by combining the ingredients and heating to 70-75°C. The oil phase shall be completely clear, and has a slight yellowish colour.

3. The oil phase is added to the water phase at 70-75°C while stirring with a planetary mixer. The mixture, that is still unstable, is stirred during 5 minutes (on a laboratory scale). Subsequently the mixture is homogenised using a high velocity rotor-sta tor mixer at maximum capacity. The pre-emulsion is cooled to 40-45°C and re-homogenised adding the preservative (Phase C). The obtained emulsion is white and is still low viscous. Upon further cooling the viscosity will continue to increase. At 25°C the fragrance is added (Phase D); stirring is continued during 15 minutes. 4. The pH is adjusted to the specifications with an 18% aqueous sodium hydroxide solution. The lotion is kept in quarantine for 5 days and committed for microbiological analysis. After 5 days the analytical data of the lotion may be adjusted to the specifications, if required. After the quarantine period the lotion may be committed for confectioning or transferred to bulk storage, provided it satisfies the specifications. INCI list: Ingredients: Aqua, Azelaic Acid, Betaine, Cetearyl Isononanoate, Cetearyl Alcohol, PEG-20 Glyceryl Stearate, Isopropyl Myristate, Steareth-2, Steareth-21, Diethylhexyl Adipate, Glycerin, Parfum, Phenoxyethanol, Sorbitan Caprylate.

Shelf life: 3 years after production, 12 months after opening. Store at ambient temperature, out of direct sun light. Preferred pack aging: tube, 30 ml.

The standard for azelaic acid in pharma & cosmetics

Phone : 0031475 782540 • info@azeco-cosmeceuticals.com • www.azeco-cosmeceuticals.com Muss nberg 1 • 6049 GZ Roermond • The N therlands

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