Azeco Cosmeceuticals

AZECO COSMECEUTICALS BV - MUSSENBERG 1, 6049 GZ Herten, The Netherlands – Phone: +31 475 206070

E NVIRONMENT Contributing Scenario 1 : Use in cleaning and maintenance products at industrial site

ERC 4, ERC 5

W ORKER Contributing Scenario 2 : Use in closed process, no likelihood of exposure Contributing Scenario 3 : Use in closed, continuous process with occasional controlled exposure Contributing Scenario 4 : Use in batch and other processes (synthesis) where opportunity for exposure arises Contributing Scenario 6 : Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at not dedicated facilities Contributing Scenario 7 : Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities Contributing Scenario 5 : Industrial spraying

PROC 1

PROC 2

PROC 4

PROC 7

PROC 8a

PROC 8b

Contributing Scenario 8 : Roller application or brushing

PROC 10

Contributing Scenario 9 : Treatment of articles by dipping and pouring

PROC 13

Contributing Scenario 10 : Lubrication at high energy conditions and in partly open process

PROC 17

3.2. C ONDITIONS OF USE AFFECTING EXPOSURE

3.2.1. C ONTRIBUTING S CENARIO 1 - C ONTROL OF ENVIRONMENTAL EXPOSURE : U SE IN WASHING , CLEANING AND MAINTENANCE PRODUCTS AT INDUSTRIAL SITE (ERC 4, ERC 5) In consideration of the chemical safety assessment, performed for this substance according to Article 14 (3) of the REACH regulation, all identified uses of azelaic acid are assessed as safe for the environment. 3.2.2. C ONTRIBUTING S CENARIO 2 - C ONTROL OF WORKER EXPOSURE : U SE IN CLOSED PROCESS , NO LIKELIHOOD OF EXPOSURE (PROC 1)

P RODUCT ( ARTICLE ) CHARACTERISTICS Covers percentage substance in the product up to 100 % A MOUNT USED ( OR CONTAINED IN ARTICLES ), FREQUENCY AND DURATION OF USE / EXPOSURE Covers daily exposures up to 8 hours T ECHNICAL AND ORGANISATIONAL CONDITIONS AND MEASURES Provide a basic standard of general ventilation (1 to 3 air changes per hour)

Use in closed process, no likelihood of exposure Advanced (industrial) exposure controls assumed O THER CONDITIONS AFFECTING WORKERS EXPOSURE Indoor use Assumes elevated process temperature up to 40.0 °C

3.2.3. C ONTRIBUTING S CENARIO 3 - C ONTROL OF WORKER EXPOSURE : U SE IN CLOSED , CONTINUOUS PROCESS WITH OCCASIONAL CONTROLLED EXPOSURE (PROC 2)

P RODUCT ( ARTICLE ) CHARACTERISTICS Covers percentage substance in the product up to 100 %.

REGULATION (EC) No 1907/2006 Date of Issue: 02/01/2020

Page 23 of 58

Date of Revision: - AZCO99 Revision Nr.: - Version Nr.: 1