Azeco Cosmeceuticals

AZECO COSMECEUTICALS BV - MUSSENBERG 1, 6049 GZ Herten, The Netherlands – Phone: +31 475 206070

S UBSTANCES IN REACH ANNEX XIV:

None.

WGK C LASS :

1 (listed as n°3013)

15.2. C HEMICAL SAFETY ASSESSMENT :

A Chemical Safety Assessment is available for this substance.

S ECTION 16: O THER INFORMATION

The present Extented Safety Data Sheet is written according to Annex II of Reg. (EC) No 1907/2006 (REACH) as amended by Annex I of Reg. (EC) No 830/2015 and is referred to the pure substance AZELAIC ACID. If the substance is used as a component of a mixture or reacted to form a new substance, the present Safety Data Sheet cannot be considered automatically as valid.

Any revision is indicated by (#).

This is an Extended Safety Data Sheet, so in its ANNEX several exposure scenarios, all relative to the uses of this substance, are reported. The table herein below contains more details of the Annex content.

T ABLE 1. O VERVIEW OF EXPOSURE SCENARIOS AND CONTRIBUTING SCENARIOS REPORTED IN THE ANNEX* E XP . S CENARIO M ARKET S ECTOR T ITLES OF EXPOSURE SCENARIOS AND THE RELATED CONTRIBUTING SCENARIOS ES1 – M1 M ANUFACTURE – M ANUFACTURE OF THE SUBSTANCE - Manufacturing of the substance (ERC 1) - Use in closed process, no likelihood of exposure (PROC 1) - Use in closed, continuous process with occasional controlled exposure (PROC 2) - Use in closed batch process (synthesis or formulation) (PROC 3) - Use in batch and other processes (synthesis) where opportunity for exposure arises (PROC 4)

- Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities (PROC 8b) - Use as laboratory agent (PROC 15)

F ORMULATION - F ORMULATION OF PREPARATIONS - Formulation (ERC 2) - Use in closed process, no likelihood of exposure (PROC 1) - Use in closed, continuous process with occasional controlled exposure (PROC 2) - Use in closed batch process (synthesis or formulation) (PROC 3)

ES2 - F1

- Use in batch and other processes (synthesis) where opportunity for exposure arises (PROC 4) - Mixing or blending in batch processes for formulation of preparations and articles (PROC 5) - Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at not dedicated facilities (PROC 8a) - Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities (PROC 8b) - Transfer of substance or preparation into small containers (dedicated filling line, including weighing) Industrial settings (PROC 9) - Production of preparations or articles by tablettings, compression, extrusion, pelettisation (PROC 14) - Use as laboratory agent (PROC 15) U SE IN CLEANING AND MAINTENANCE PRODUCTS AT INDUSTRIAL SITE - Use in cleaning and maintenance products at industrial site (ERC 4, ERC 5) - Use in closed process, no likelihood of exposure (PROC 1) - Use in closed, continuous process with occasional controlled exposure (PROC 2) - Use in batch and other processes (synthesis) where opportunity for exposure arises (PROC 4) - Industrial spraying (PROC 7) - Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at not dedicated facilities (PROC 8a) - Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities (PROC 8b) - Roller application or brushing (PROC 10) - Treatment of articles by dipping and pouring (PROC 13)

ES3 - IW1 PC 35 PC 20

REGULATION (EC) No 1907/2006 Date of Issue: 02/01/2020

Page 11 of 58

Date of Revision: - AZCO99 Revision Nr.: - Version Nr.: 1